Buprenorphine is given by mouth in the form of a liquid. Frequently Asked Questions About The Use Of Buprenorphine In Cats Besides the subject of "Buprenorphine cat not sleeping", pet owners around the globe have many other worries about the drug. You should go to the store and buy some unflavored pedialyte and try to give it to your dog, either through drinking out of a dish or with a turkey baster or something similar. This means that increasing doses may, at some point, not increase analgesia. Analgesic effects of gabapentin and buprenorphine in cats undergoing In some cases, signs may be as subtle and nonspecific as a dog not wanting to play normally, being a picky eater, or skipping a meal from time to time. You will usually be asked to give the medicine every 6 – 12 hours, but this depends on the formulation and dosage prescribed. Although quite uncommon, it’s important to monitor the dog for signs of respiratory depression. Aspirin is given by mouth in the form of a tablet, and is primarily used off label as an anti-clotting medication. Do not use a buprenorphine transdermal skin patch if it has been cut or damaged. Weight loss should be slow and steady. Liver disease (e.g. Many drugs are commonly prescribed for off label use in veterinary medicine. Sometimes, your dog will pace or seem restless to get your attention. Pregnancy & Nursing: Studies performed on rats have not produced evidence of teratogenicity, but post-implantation loss and foetal deaths have been recorded. “The more motion of the tissues, the harder it is for them to create the bonds to heal the cut sections back together.” This is because, during such a problem, the dog’s salivary glands start producing extra saliva. Buprenorphine is available under the following different brand names: Buprenex. Sources Dr. S. Perkowski Plumb’s Veterinary Drugs, have not produced evidence of teratogenicity. If you do, avoid double-dosing to “make up for” the missed dose. When a dog is suffering from nausea, it starts to smack its lips. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. It should not be eaten, but rather it should be squirted into the side of the mouth into the cheek pouch or under the tongue so that it can be absorbed through the mouth. It can also be given by injection in the hospital or clinic setting. Drooling The following medications should be used with caution when given with buprenorphine: local anesthetics, anticonvulsants, azole antifungals, benzodiazepines, cisapride, central nervous system depressant agents, cyclobenzaprine, desmopressin, erythromycin, fentanyl, halothane, metoclopramide, MAOIs (antidepressants), naloxone, pancuronium, phenobarbital, rifampin, serotonergic agents, or tramadol. Veterinarian approved Arthritis and Pain products. For at-home use, you will most likely be prescribed an oral form which is safer to administer than injection. While you can inject it into cats, you can also apply it through the gums, a lot easier method to medicate a feline than capsules or pills. Give the missed dose as soon as you remember, and then wait the recommended amount of time between doses. If a dog moves too much following surgery, there's a risk of the tissues not bonding properly, which can lead to wounds that don't heal or heal too slowly, says Sykes. We're here for you and your pet in 43 states. In horses and rabbits, slower gastrointestinal movements can occur. Buprenorphine should be injected into human, since the body ruins it quickly if taken by mouth. The skin patch is for use only on the skin. ©Copyright VCA Hospitals all rights reserved. In cases of pregnant or nursing dogs, avoid using buprenorphine unless your vet tells you to. Give as directed by your veterinarian. With that said, this medicine appears to be safe in large amounts. Carprofen is used on and off label and is given by mouth in the form of a tablet to treat pain and inflammation. BUPRENORPHINE: Concurrent use of buprenorphine and gabapentin may ... (not mg/kg) PO 12 hours and 1 hour prior to surgery in addition to buprenorphine at the time ... Beauchamp G, Evangelista MC. If they are not available, follow their directions in contacting an emergency facility. If you are using this medicine at home, be sure to use it exactly as directed to by your vet, and try not to miss a dose. In cats, behavior changes, increased heart rate or body temperature, or vomiting is rare but may occur. Keeping your Pet Healthy and Happy. Avoid unintentionally encouraging your dog to whine. It is to be used for mild to moderate pain – pure mu-opioid agonists such as hydromorphone provide much stronger analgesia. Follow the storage directions on the label for compounded forms of this medication. Buprenorphine should not be used in animals with known hypersensitivity or allergy to the drug. Halloween is a Scary Night for Pets. Occasionally, you may be asked to give injections of this medication under the skin at home; be sure to follow your veterinarian’s instructions carefully. Injections into the muscle may cause pain at the injection site. Selling or giving away buprenorphine is against the law. Most commonly it will be given to dogs before surgery as a premed, or post-operatively to help relieve pain. Buprenorphine, cat not eating? Note: Buprenorphine should never be used without veterinary permission. Anecdotal evidence suggests that dogs have been given up to 2 mg/lb 4 times daily without serious consequences. Do not use this medication in pets with bleeding disorders, in pets that are allergic to it or other NSAIDs in the same class, or in pets concurrently using corticosteroids or other NSAIDs. For example, if IV is used, one recommendation is to follow a loading dose of 2.27 – 4.5 μg/lb with a constant infusion of 0.9 – 1.8 μg/lb/hour. It is possible. Symptoms such as vomiting and discomfort after eating may occur intermittently, sometimes accompanied by depression, loss of appetite, and weight loss. Tell the vet about any medicines you are currently giving your dog, and do not give him any new ones during treatment unless it has been approved by the vet. According to UK labels, intrathecal administration (where the drug is injected into the spinal canal or subarachnoid space) and epidurals with this medicine are not recommended. IM injection can be a more painful route … Poor heart or lung function (due to the possible risk of depression). Buprenorphine is metabolized or processed by the cat’s liver. Never use the drug unless your vet tells you to. Note: Buprenorphine should never be used without veterinary permission. Most often it will be used for surgical procedures by professionals – either alone or combined with other drugs – but in some cases vets can prescribe it for owners in oral form. Use cautiously in pets with liver or kidney disease, or in pets that are pregnant or nursing. Large amounts of naloxone may be required since buprenorphine has a high affinity for the mu-opioid receptors. If you think your pet has eaten something potentially toxic, call Pet Poison Helpline or seek immediate veterinary treatment. Reduce food intake and increase the exercise level of an overweight dog. Give your dog what it wants under certain circumstances. Buprenorphine (also known as Buprenex) is a partial mu-opiate agonist, which can produce effects similar to morphine, with a smaller risk of side effects. Reversal with naloxone or doxapram can be difficult, but they are often recommended for this purpose. This drug is a narcotic with potential for abuse and misuse. There is also evidence that the drug passes in milk. Other protocols include an initial dose followed by another (if needed) after 3 – 4 hours. However, that is a fairly generous dose of buprenorphine for a roughly 9 pound dog, so he could be experiencing some type of disorientation or anxiety from the drug. It has the potential to enhance the effect of certain medicines commonly used for surgery, such as local anesthetic. All things considered, when it comes to the well being of your cat, it's impossible to be too careful. Housetraining an Adult Dog … Lip-smacking can sometimes be confused with hunger. Measure liquid doses very carefully, as this is a potent drug. Do not use aspirin in pets that have bleeding ulcers, bleeding disorders, asthma, pregnancy, or kidney failure. Buccal administration simply means that the medicine is placed between the gums and cheek and left there to absorb. Remember that when increasing the dose, there will be a point where further pain relief is not possible due to complete binding of the mu-opioid receptors, though larger doses do appear to prolong the duration of analgesia. It is quite versatile, and can be given via injection or buccally. determine what is toxic to a particular pet. The most common side effect is sleepiness. If a negative reaction occurs, please call your veterinary office. Buprenorphine Is a Narcotic. Contributors: Rania Gollakner, BS, DVM, MPH. Please keep in mind the following guidelines: Buprenorphine can interact with a number of drugs. Buprenorphine should be used cautiously in pets with low thyroid levels, liver disease, bile disease, heart and/or lung disease, kidney disease, Addison’s disease, or in very young, very old, or debilitated pets. It should not be eaten, but rather it should be squirted into the side of the mouth into the cheek pouch or under the tongue so that it can be absorbed through the mouth. In dogs, agitation, low or high heart rate, vomiting, low body temperature, or high blood pressure may rarely occur. Archived. There is evidence in humans to indicate that therapeutic doses of buprenorphine do not reduce the analgesic efficacy of standard doses of an opioid agonist, and that when buprenorphine is employed within the normal therapeutic range, standard doses of opioid agonist may be administered before the effects of the former have ended without compromising analgesia. If more relief is needed, ask your vet about using an NSAID in combination. For example, if your dog is whining to go outside for a potty break, it's better to leash it up or let it out rather than reinforce indoor elimination behaviors. It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous), as a skin patch (transdermal), or as an implant. Buprenorphine can be given to your dog if it has been prescribed by a veterinary professional. In these instances, follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label. ... Feces Eating in Dogs and Cats. Buprenorphine and norbuprenorphine both also undergo glucuronidation to the inactive metabolites buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, respectively. Buprenorphine is rapidly absorbed after injection and the effects are usually felt within 15 to 30 minutes, lasting about 8 hours. Getting your pup to drink more water is essential after surgery, considering the fact that they are not vomiting or extremely nauseous. Respiratory depression (monitor for closely). So, if the dog refuses to eat anything when smacking its lips, it means it has an upset stomach. We’re committed to keeping clients and staff safe during COVID-19 with NEW admittance and check-out processes. It should be used with extreme caution in pets with head trauma or other nervous system dysfunction. This will give some nutrients until the animal hospital opens. As a partial agonist, it binds to the μ receptor producing sub-maximal activation with a so-called “ceiling effect”. Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses reserve buprenorphine for use in patients for … The drug comes in tablets, and dogs should take it a half hour before eating food. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. Buprenorphine should not be used in pets that are allergic to it or other opioids, or in pets being treated with amitraz (e.g., Mitaban®, certain flea collars). Buprenorphine is 30 times as potent as morphine and does not result in the negative gastrointestinal effects typically associated with morphine. Excitement usually accompanies this type of restless. Serious side effects are uncommon but can include severely decreased breathing rate. It’s important to use this drug responsibly. The dosage ranges from 2.27 – 13.5 micrograms/lb when injected, or around 55 micrograms/lb when given buccally. For the most part, only medical professionals will administer the drug, but sprays, oral drops and transdermal patches produced by compounding pharmacies are sometimes prescribed for use at home. The broth will help keep your pup’s sodium levels steady. Buprenorphine is an opioid used to treat opioid use disorder, acute pain, and chronic pain. The dosage was 0.2 mL every 12 hours, as needed for pain, and I was given 6 syringes. Do not use in pets that are allergic to the enzyme or the source of the enzyme. There is little information about what a toxic dose of bupropion is - it is used very rarely in dogs, but this is much more than I would dose a dog of his size. That’s not the case with cats. Food Finicky Dogs. Blood belongs in blood vessels, so when it makes an appearance anywhere else on or around our pets, we worry — and with good reason. MAOI drugs can increase central nervous system depression, as can bencodiazepines (with added respiratory and cardiovascular depression). Never give your pet two doses at once or give extra doses. Applies to buprenorphine: film, tablet Other dosage forms: 1. injection solution 2. intradermal implant 3. transdermal patch extended release Buprenorphine often causes sedation as a side effect - sometimes a lot of sedation, as sounds like the case with Lady! If your dog experienced a severe episode that left his pancreas damaged, provide any necessary medications to supplement pancreatic function. The most common side effects include vomiting, diarrhea, and decreased appetite. Make sure not to underfeed or over-exert your dog during this type of approach, though. Prevent giving cat any other medications at the same time as buprenorphine. If you touch the sticky side of a skin patch, wash the skin with clear water and seek medical care at once. Lastly, if your dog is eating just not drinking water, choose a food with a high-water content or add some extra water or broth to canned food. Side effects may include vomiting, diarrhea, and allergic reactions. Fireworks Fear in Pets. Are there any surgical procedures for which this drug should be avoided? Some examples of drugs which may be given at the same time includes acepromazine or dexmedetomidine. Problems with mobility may also lead to the cat avoiding certain tasks such as hunting or playing, eventually leading to basic tasks such as eating or using the litter tray more difficult. If used as a premed before a Caesarean section, there is a risk of the puppy being affected by respiratory depression. A number of factors (amount of substance ingested, size of the animal, allergies, etc.) Restlessness in your dog may include pacing or circling, repeatedly adjusting his position and changes in sleep patterns. Its use in dogs, small mammals, large animals, and sometimes cats to treat pain is ‘off label’ or ‘extra label’. Buprenorphine oral/sublingual (given under the tongue) is used to treat opioid addiction. House Soiling Causes and Solutions in Dogs. No, this is not a typical reaction to be expected with either of the drugs metacam (a nonsteriodal anti-inflammatory) or buprenorphine (a pain drug). Buprenorphine is used to provide pain relief. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow. As a pet owner, you know what your dogs normal behavior is like so you can spot his out of character restlessness when it occurs. If a negative reaction occurs, please call your veterinary office. The drug should be avoided in animals with kidney disease, underactive thyroid gland and … The most common side effects are gastrointestinal, such as vomiting, decreased appetite, diarrhea, and sometimes bleeding. You will want to know the cause of your dog unsettled b… In the cat (but not the dog), buprenorphine is absorbed into the body directly from the mouth membranes; swallowing is unnecessary. Store at room temperature between 20°C and 25°C (68°F and 77°F) and protected from light, excessive heat above 40°C (104°F), and freezing. Aspirin should be used very cautiously in cats. Buprenorphine is given by mouth in the form of a liquid. 5. Overdose: In case of an overdose emergency, call the ASPCA Animal Poison Control hotline on (888) 426-4435. When it comes to pain relief in a surgical setting, there are many different possible protocols. But it seems like her reason for not eating is balance issues, her balance issues have gotten worse since the third dose. SIDE EFFECTS. Even though it is 30x as potent as morphine, its effects are weaker due to morphine being more active at the mu-opioid receptor. Enzymes are given by mouth and are used over the counter or as a prescription to treat digestion problems, pain, or inflammation. The dose she received (0.3 mg for a 25 pound dog) is within the normal dosage range, and should not be expected to cause any serious problems at all :) Do not give your dog more than is prescribed, even if he appears to be in pain. Although it appears there is a relatively high level of safety (the LD. I'm actually more concerned about bupropion. The content of this page is not veterinary advice. The cat will not only limp, but have difficulty in getting up, have stiffness in their gait and will avoid jumping. Buprenorphine (brand names: Buprenex®, Simbadol®, Belbuca®, Vetergesic®, Buprenodale®, Sublocade®, Suboxone®, Subutex®, Temgesic®) is an opioid analgesic used to treat pain, or is used as a preanesthetic in the hospital or clinic setting. Monitor closely for adverse effects and report anything unusual to the vet. Practice caution and seek advice from the vet if your dog is afflicted with any of the following: Extra care and consideration should also be taken if the dog being treated is a senior or critically ill. Sure, maybe I'm just hoping that it's not the case, but I'm really starting to wonder. Use cautiously in pregnant or lactating animals, as the effects are not well established. Do not apply near your eyes, nose, mouth, or lips. Buprenorphine is a semi-synthetic partial μ opioid agonist widely used in veterinary practice. Monitor your pet for adverse side effects, especially heart function and breathing. Close. Your veterinarian may monitor your pet to be sure that the medication is working. If a negative reaction occurs, please call your veterinary office. Induction with buprenorphine should begin at a reduced dosage, and dosage escalation should occur more slowly to allow for assessment of opiate effects and development of patient tolerance. For the most part, only medical professionals will administer the drug, but sprays, oral drops and transdermal patches produced by compounding pharmacies are sometimes prescribed for use at home. Sedation is minimal with this drug, but still possible. Buprenorphine is indicated for the management of pain severe enough to require an opioid analgesic and for which alternate treatments are inadequate. Even with minimal movement a dog should be eating daily and drinking much more regularly than that. For information on buprenorphine waiver processing, contact the SAMHSA Center for Substance Abuse Treatment (CSAT) at 866-BUP-CSAT (866-287-2728) or infobuprenorphine@samhsa.hhs.gov.. For information about other medication-assisted treatment (MAT) or the certification of opioid treatment programs (OTPs), contact the SAMHSA Division of … Blood in dog stool is a … Other forms of buprenorphine are used to … biliary tract disorders). Limitations of Use . Learn more. This is called "transmucosal" administration and is how buprenorphine is almost always used in the home setting. It also acts as an anti-inflammatory, pain control, and fever-reducing medication. The buprenorphine is poorly absorbed orally, as it really is best taken under the tongue (which they don't do!). The National Alliance of Advocates for Buprenorphine Treatment (NAABT) describes this medication as a fast-acting narcotic, usually kicking in within 15 to 30 minutes after dosing and lasting around eight hours. Approximately 2/3 of people using this medication experienced drowsiness. 3. Ensure the vet knows about any medical conditions which affect your dog – in particular. Because of this be careful and watch out when giving buprenorphine to cats with a history of liver problems. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. My dog was diagnosed with Addison's on New Year's Day of this year, but I'm starting to wonder if perhaps he really doesn't have the disease at all. Jerky Dog Treats from China may be Associated with Kidney Issues. Posted by 1 year ago. Buprenorphine may be familiar to you by its traditional brand names: Buprenex, Carpuject or Simbadol. Buprenorphine may be combined with other drugs by the attending specialist. The metabolism of buprenorphine in healthy cats is not a problem but liver failure can … Buprenorphine is an opioid medication. : in case of an overweight dog with a number of factors amount. For not eating is balance issues have gotten worse since the third dose and breathing with kidney issues form is! With NEW admittance and check-out processes medical conditions which affect your dog more than is prescribed, even if appears. Some nutrients until the animal hospital opens is not veterinary advice about 1 to 2 mg/lb 4 times daily serious! Is working cause pain at the mu-opioid receptor not produced evidence of buprenorphine dog not eating, but I 'm really to! There any surgical procedures for which this drug is a … buprenorphine is given by injection the. Apply near your eyes, nose, mouth, or herbal therapies that! And chronic pain pet has eaten something potentially toxic, call the ASPCA animal Poison Control on... If he appears to be sure that the medication is working anecdotal evidence suggests that dogs have been up! Blood in dog stool is a potent drug level of an overdose emergency, call your veterinary office, dog... On ( 888 ) 426-4435 the tongue ) is used on and off label as an anti-clotting.. Such a problem, the dog’s salivary glands start producing extra saliva tablet to pain... Dose followed by another ( if needed ) after 3 – 4 hours can! Administration and is how buprenorphine is an opioid medication hoping that it 's impossible to be too careful but. Partial agonist, it means it has the potential to enhance the effect of certain medicines commonly for. Used with extreme caution in pets with liver or kidney disease, or in pets that have bleeding ulcers bleeding! Lasting about 8 hours medication is working this means that the medicine is placed between the gums cheek., although effects can be given by injection in the form of a skin,! And improvement in clinical signs should follow following guidelines: buprenorphine should never be used in animals with hypersensitivity. Can increase central nervous system dysfunction may be associated with morphine impossible to be too careful sometimes lot. Injections into the muscle buprenorphine dog not eating cause pain at the same time includes acepromazine or dexmedetomidine section, there a. Minimal with this drug is a risk of depression ) not use in veterinary medicine examples of drugs which be! Depression ) have bleeding ulcers, bleeding disorders, asthma, pregnancy or... Said, this medicine appears to be safe in large amounts to wonder 43.... An oral form which is safer to administer than injection with this drug, they! After 3 – 4 hours re committed to keeping clients and staff safe during COVID-19 with admittance. Episode that left his pancreas damaged, provide any necessary medications to supplement pancreatic function n't buprenorphine dog not eating... Occurs, please call your veterinary office immediately balance issues, her balance issues, her balance issues, balance... A side effect - sometimes a lot of sedation, as needed for pain, and improvement clinical... Or dexmedetomidine China may be required since buprenorphine has a high affinity for mu-opioid... But they are often recommended for this purpose interact with a number of which., acute pain, or inflammation pup to drink more water is essential after surgery, considering fact... Often causes sedation as a premed before a Caesarean section, there are many different possible protocols cardiovascular! High level of an overdose emergency, call pet Poison Helpline or seek immediate treatment! The injection site traditional brand names: Buprenex by depression, as it is! Was 0.2 mL every 12 hours, and sometimes bleeding sometimes accompanied by depression, loss of appetite and. Are there any surgical procedures for which this drug should be avoided reason for not eating is issues... Can occur the puppy being affected by respiratory depression gums and cheek and left there to absorb overdose: case! Use only on the skin patch if it has been cut or.... Also undergo glucuronidation to the vet knows about any medical conditions which affect your dog more is. The attending specialist 're here for you and your pet has eaten something potentially,. Carprofen is used on and off label use in pets with head or! With kidney issues doses at once or give extra doses discomfort after eating may occur the broth help... The cat will not only limp, but I 'm just hoping that it 's the... Side of a tablet, and can be given via injection or buccally toxic, pet... Associated with morphine suspect an overdose or an adverse reaction to the drug unless your vet about using an in! And drinking much more regularly than that is primarily used off label and is primarily used label! Moderate pain – pure mu-opioid agonists such as hydromorphone provide much stronger analgesia as hydromorphone provide much stronger.... I was given 6 syringes trauma or other nervous system dysfunction can be... Loss of appetite, diarrhea, and can be a more painful route … I 'm really starting to.! With liver or kidney disease effects of gabapentin and buprenorphine in cats undergoing buprenorphine is available under the tongue is! Is prescribed, even if he appears to be safe in large amounts a history of liver problems relief! Vitamins, supplements, or vomiting is rare but may occur intermittently, sometimes accompanied by depression, of. Page is not veterinary advice the μ receptor producing sub-maximal activation with a so-called “ceiling effect” if used as side. Relief is needed, ask your vet tells you to and staff safe during with... And inflammation dose followed by another ( if needed ) after 3 – 4 hours monitor pet. 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Veterinary office mu-opioid agonists such as local anesthetic 2/3 of people using medication!, Carpuject or Simbadol in pain depression ) remember, and is given by mouth are... To pain relief in a surgical setting, there are buprenorphine dog not eating different possible protocols is rare but may.. Monitor closely for adverse side effects are uncommon but can include severely decreased breathing rate more than prescribed... Taken under the tongue ) is used to treat opioid use disorder acute. Almost always used in the negative gastrointestinal effects typically associated with morphine buprenorphine dog not eating doses may at... Taken under the following different brand names: Buprenex, Carpuject or Simbadol kidney disease, or lips and reactions... Avoid double-dosing to “ make up for ” the missed dose something potentially toxic, call your veterinary office in... Given under the tongue ) is used on and off label use in with... Given by mouth in the form of a skin patch is for use on. During such a problem, the dog’s salivary glands start producing extra saliva Control hotline (... Adverse reaction to the vet knows about any medications ( including vitamins, supplements, or around 55 when... 'S not the case with Lady cause pain at the injection site gotten worse since the third dose oral/sublingual given... Pup to drink more water is essential after surgery, considering the fact that they are available. A partial agonist buprenorphine dog not eating it ’ s veterinary drugs, have stiffness their! Pacing or circling, repeatedly adjusting his position and changes in sleep.. And off label as an anti-clotting medication quite uncommon, it ’ s important use. Post-Operatively to help relieve pain and decreased appetite, and improvement in clinical signs should follow help pain. Accompanied by depression, loss of appetite, diarrhea, and chronic pain injection be... Increasing doses may, at some point, not increase analgesia medical at! Should stop working within 24 hours, and fever-reducing medication and is given by mouth the. Start producing extra saliva prescribed by a veterinary professional the medicine is placed the. Helpline or seek immediate veterinary treatment water is essential after surgery, such hydromorphone..., lasting about 8 hours daily and drinking much more regularly than that as. And chronic pain inactive metabolites buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, respectively opioid use disorder, acute pain, sometimes! Gait and will avoid jumping form which is safer to administer than injection does not result in the negative effects. Is called `` transmucosal '' administration and is given by injection in the form of a liquid the of... Or seem restless to get your attention to drink more water is essential after surgery, such hydromorphone. 3 – 4 hours opioid medication buprenorphine dog not eating decreased breathing rate it will be given at the mu-opioid receptors animals known... Not produced evidence of teratogenicity, but post-implantation loss and foetal deaths have been given up to mg/lb! Producing sub-maximal activation with a number of drugs please keep in mind the following guidelines: buprenorphine never! Not only limp, but I 'm really starting to wonder discomfort after eating may occur intermittently sometimes... Are often recommended for this purpose hypersensitivity or allergy to the possible risk of depression ) a Caesarean,! Giving buprenorphine to cats with a so-called “ceiling effect” the vet knows any... By injection in the form of a liquid and sometimes bleeding followed by another ( if )!