* Fiproclear 402mg spot-on solution for very large dogs (40-60kg): 1 pipette of 4.02ml is sufficient for the treatment of a dog with a body weight of 40kg up to 60kg corresponding to a recommended minimum dose of 6.7mg fipronil/kg body weight. DOSAGE AND ADMINISTRATION: For 100 ml, Hold the bottle in upright position. Featured Fact: Did you know EFFIPRO PLUS Topical Solution for Dogs dual action of fipronil and pyriproxyfen effectively breaks the flea life cycle? “Frontline Top Spot” is not recommended for use in debilitated or geriatric animals. Dose is 0.05ml/pound. Dosing Information of Fipronil and Methoprene for Dogs and Cats Medication should never be administered without first consulting your veterinarian. While generally safe and effective when prescribed by a veterinarian, fipronil and methoprene can cause side effects in some animals. Fipronil is a topical agent and temporary irritation at the site of application is possible. The chronic reference dose (RfD) for fipronil is 0.0002 mg/kg/day based on the NOAEL for chronic toxicity ... A spot-on treatment study with 14 C-fipronil on dogs and cats found that radio-labeled fipronil was distributed primarily in the superficial skin layers. Different doses are available, and you choose the correct one based on the weight of your Lab. National regulatory authorities determine whether a product is approved for a given indication , i.e. 95. The highest dose was reduced to 2 mg/kg bw per day after 38 days because of toxicity. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Ivermectin for cattle *2. Other options New from $33.13. Ruffle the animal’s coat while applying spray mist to its body. Fipronil. Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole chemical family. $33.95 $ 33. This drug is registered for use in animals only. Eighteen dogs were randomly assigned to the following treatment groups (n = 6): (1) 65% permethrin, (2) 9.7% fipronil, or (3) untreated control. Mange and adjunct to myiasis therapy . The risk of adverse effects may increase in cases of overdose. All Hello, Sign in. Mean drug dosage for all dogs was approximately 2 mg/kg body weight. No adverse effects were observed in target animal safety studies in 2 month-old puppies, growing dogs and dogs weighing about 2 kg treated with the therapeutic dose on five consecutive days. EFFIPRO PLUS ® Topical Solution for Dogs contains the active ingredient fipronil, which controls infestations caused by fleas, ticks and chewing lice on dogs or puppies 8 weeks old or older weighing 45-88.9 lbs. DOSAGE: CONCENTRATION: FOR DOGS WEIGHING Frontline® Plus for Dogs (Orange Box) UK Version, VMD MA Vm 08327/4211: 0.67 mL: 100 g/L Fipronil & 90 g/L (S)-Methoprene: Up to 10kg : USA Version, EPA Reg. This causes hyperexcitation of contaminated insects' nerves and muscles. Fipronil is available in a topical 9.7 percent solution. In Dogs, fipronil’s major metabolite on the haircoat of the dog and in the blood stream is the sulfone derivative. Fipronil is also available in a 0.29 percent topical spray, in a 100 ml bottle or 250 ml bottle. Spot-on treatments are pre-measured doses in single use pipettes, which you empty onto the back of your dog’s neck. PHARMACEUTICAL FORM. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with fipronil. See packaging for complete product details. However, if your dog weighs more than 132 pounds, you’ll need to combine products to get the correct dosage. Concerns About Fipronil. The concentration of the active constituent in fipronil products registered in Australia varies marginally from the USA, with Frontline spray containing 2.5 g/L (0.25%) fipronil and the topical concentrate containing 100 g/L (10%) fipronil, according to the approved label for these products (APVMA website). Effipro also provides a more flexible solution than traditional flea and tick treatments, as you can purchase as many or a few pipettes as you require to treat your pets. 100.00%. Le fipronil a été mis au point en France par la société Rhône-Poulenc en 1987 et mis sur le marché en 1993. • Technical grade fipronil is considered moderately toxic by inges-tion with an oral LD 50 of 97 mg/kg in rats and an LD 50 of 95 mg/ kg in mice.1 See the text boxes on Toxicity Classification and LD 50 /LC 50. Animals with long hair need the higher dose. When you dog has been given too much medicine, it is called an overdose (just like it is for humans) and overdoses can be fatal! Each card contains 3 or 6 pipettes. dogs 10-20 kg ; 2.14 . KEEP OUT OF REACH OF CHILDREN. It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. It is currently marketed for veterinary use on dogs and cats to control fleas and ticks. GI parasites, levamizole drug of choice for lungworm . Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. Category: Pet Supplies | Last Updated: 2020-01-01 20:56:22 by Kailee Hagenes. This drug is registered for use in animals only. OTHER INGREDIENTS. The "Plus" is … Ivermectin. | P TOTAL: 100%. mals each were formed. Fipronil (brand names: Frontline®, Barricade®, Easyspot®, Effipro®, Sentry Fiproguard®, Parastar®, PetArmor®, Pronyl OTC®, Spectra Sure®, and many others) is a topical medication used to treat fleas, ticks, and chewing lice infestations in dogs and cats. States in 1996 than 8 weeks of age or older with 5 fipronil for dogs dosage dose sizes for dogs 60kg. 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